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pyCircAdapt

Programmatic access to the complete CircAdapt model for in silico research

pyCircAdapt provides programmatic access to the full CircAdapt model for in silico cardiovascular research. It supports custom simulation design, hypothesis testing, model coupling, and automated analysis workflows, with full control over model structure and parameters. The framework is distributed as a Python package (wheel) with access to the underlying source code, enabling extension, customisation, and integration into larger computational pipelines.

Designed for

Simulating cardiovascular physiology and pathophysiology to study system-level responses under varying conditions

Testing hypotheses on disease mechanisms and physiological substrates in silico

Evaluating virtual therapies and intervention strategies

Coupling with other models and developing patient-specific simulations

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pyCircAdapt is distributed as a Python package with access to the underlying source code, available to registered academic researchers under the CircAdapt Framework licence with attribution. Installation instructions and API documentation are provided through framework.circadapt.org. When pyCircAdapt is used in published work, please cite the relevant key publications.

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